Overview
 

Reducing Harm: Treatment and Beyond

Maintenance Therapies

Drug substitution and maintenance approaches have a long history. These involve providing drug addicts with legal access to drugs that would otherwise be obtained through illegal means. The basic rationale is that of harm reduction: if some people are unable to quit using drugs, both users and society at large benefit if these users, i.e., addicts, are able to switch from "black market" drugs of indeterminate quality, purity and potency to legal drugs, of known purity and potency, obtained from physicians, pharmacies and other legal channels. The risks of overdoses and other medical complications decline; the motivation and need for addicts to commit crimes to support their habits drop; addicts are more likely to maintain contact with drug treatment and other services, and more able and likely to stabilize their lives and become productive citizens. In the United States, morphine maintenance clinics proliferated during the first two decades of this century, before being closed under pressure by law enforcement authorities.

The most famous U.S. clinic, the Shreveport Clinic, operated in Louisiana from 1919 to 1923. The clinic enjoyed the support of federal and city judges, local law enforcement and pharmacists, all of whom, fearing an increase in crime, opposed efforts by federal narcotics agents to close the clinic. The practice of prescribing heroin to addicts was standard in England from the 1920s to the 1960s. In response to political pressure from the U.S., heroin maintenance was severely curtailed in 1971 when passage of the Misuse of Drugs Act added burdensome regulations. Government disapproval led to a sharp decline in the practice among private physicians. The loss of a controlled distribution system and subsequent creation of an unregulated illicit market allowed the number of heroin users to skyrocket from fewer than 2,000 in 1970 to upwards of 300,000 today. What was once discouraged is now being promoted in England, in large part due to a perceived increase in heroin-related crime.

Maintenance therapies made a comeback in the U.S. during the mid-1960¡¯s with the advent of methadone, a synthetic morphine substitute discovered by German scientists during World War II. Methadone maintenance is now widely regarded as the most effective known treatment for heroin addiction. Used properly, methadone reduces drug use and related crime, death, and disease among heroin users. But methadone has been handicapped by restrictive government regulations, by misinformation - among treatment providers and drug users alike - and by prejudice against methadone treatment. Methadone is the most tightly restricted drug in the U.S. Doctors in general medical practice can't prescribe methadone, and regular pharmacies don't distribute it.

The most dramatic development in drug substitution and maintenance is now underway in Switzerland. On July 10, 1997, the government announced the results of a three-year experiment in which 800 heroin addicts were maintained on legal prescriptions of heroin, and a much smaller number on injectable morphine and methadone. The promising results of the Swiss trials have led to ongoing pilot projects involving heroin maintenance in Germany, Spain and the Netherlands. In December 2002, the Canadian House of Commons Special Committee on Non-Medical Use of Drugs called for ¡°proposed clinical trials pilot project in Vancouver, Toronto and Montreal to test the effectiveness of heroin-assisted treatment for drug-dependent individuals resistant to other forms of treatment.¡± In Australia two phases of a proposal to initiate a heroin prescription experiment in the Australian Capital Territory (Canberra) were approved in late July, 1997, but continue to face strong opposition from some members of the government.